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Positron emission tomography (PET) is a diagnostic nuclear medicine technique, in which positron-emitting radiopharmaceuticals are administered to the subject and the activity distribution is imaged with a PET camera. The PET provides assessment of regional organ functions (blood flow, metabolism, receptors, etc.), which is promising for elucidating physiology, pathophysiology and biochemistry and diseases.

  1. Positron Emission Tomograph (for human)
  2. Positron Emission Tomograph (for small animals)
  3. Compact Cyclotron
  4. Labeled Compounds Synthesizer

1. Positron Emission Tomograph (for human)

A photo of the Positron Emission Tomograph (for human).

The aim of adopting this system are development and practice the visualization method of specific membrane proteins behavior in the human brain. This is a positron emission tomograph (PET camera) in conjuction with a X-ray computed tomograh (CT scanner) in the same gantry.


2. Positron Emission Tomograph (for small animals)

A photo of the Positron Emission Tomograph (for small animals).

This is a compact PET system applying for small animals, which have high spatial resolution (1.6mm) and high detection sensitibity. This systems is used to visualize the physiological process in the small animals, and to develop pharmaceuticals and biological research by the pharmacokinetic analysis with the radiopharmaceuticals, which is a specific binding in the brain.


3. Compact Cyclotron

A photo of the Compact Cyclotron.

This is a negative ion acceleration type compact cyclotron, which produces positron emitters (11C, 18F, 15O, and so on) utilizes protons (16.5MeV) and deuterons (8.4MeV).


4. Labeled Compounds Synthesizer

A photo of the Labeled Compounds Synthesizer.

This systems syntheses positron emitting radiopharmaceuticals, such as 15O-H2O, 15O-CO2, 15O-O2, 15O-CO.

An outside view of the hot cell.

The automated synthesizers for the other positron emitting isotopes (11C and 18F), are placed in the hot cell which is protecting the operators from radiations.

The inside of the hot cell.

The one of synthesizers makes a purposive positron emitting radiopharmaceutical, such as 18F labeled Fluoro-D-Glucose ([18F]FDG), for each PET studies.




Copyright © 2017 Center for Integrated Human Brain Science, University of Niigata.
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